Chicago Cubs vs St. Louis Cardinals Prediction, Odds, and Pitching Matchup: Imanaga vs. Gray – August 10, 2025

Sunday, August 10th, 2025

Chicago Cubs at St. Louis Cardinals MLB Game Preview – August 10, 2025

Series Overview

The Chicago Cubs (67-49, second in the NL Central) will face off against the St. Louis Cardinals (59-59, fourth in the NL Central) at Busch Stadium, with the three-game series tied at 1-1. This game will be the 10th meeting between these divisional rivals this season, and the Cubs currently lead the series 5-4.

Weather

Today at Busch Stadium, expect warm and mostly sunny conditions, with temperatures reaching the upper 80s. There's little chance of precipitation, making rain delays unlikely. Light southwest winds around 7 mph should have minimal impact on gameplay, contributing to ideal baseball weather.

Pitching Matchup

The Cubs are expected to start Shota Imanaga (8-4, 3.12 ERA, 1.00 WHIP, 70 strikeouts), while the Cardinals will send Sonny Gray (10-5, 4.21 ERA, 1.17 WHIP, 141 strikeouts) to the mound. Oddsmakers have the Cubs favored at -124, with the Cardinals at +104, and an over/under of 8 runs for the game.

Team Performance

St. Louis boasts a 33-25 record at home and is 44-10 in games when scoring at least five runs. The Cubs, with a 31-27 record on the road, have excelled when showing power at the plate, going 35-11 when hitting at least two home runs in a game.

Players to Watch

For the Cardinals, Willson Contreras leads the team with 16 home runs and holds a .450 slugging percentage. Jordan Walker has been hot lately, going 12-for-37 with a double, a home run, and five RBI over the last 10 games.

Pete Crow-Armstrong highlights the Cubs with 31 doubles, four triples, 27 home runs, and 78 RBI while hitting .258. Nico Hoerner is also finding success at the plate, batting 11-for-37 with a double and a home run over his last 10 contests.

Recent Performance

Over the past 10 games, the Cardinals have a 4-6 record, with a team batting average of .241 and a 4.66 ERA, being outscored by 17 runs. The Cubs are 5-5 in their last 10, hitting .242 with a 3.27 ERA, and have outscored opponents by six runs in that span.

Injuries

Cardinals: Brendan Donovan is day-to-day with a groin injury. Nolan Arenado is on the 10-day IL with a shoulder injury, John King is on the 15-day IL with an oblique issue, and Zack Thompson is on the 60-day IL with a lat injury.

Cubs: Mike Soroka (shoulder) and Jameson Taillon (calf) are on the 15-day IL. Miguel Amaya (oblique), Eli Morgan (elbow), Javier Assad (oblique), and Justin Steele (elbow) are all on the 60-day IL.

In summary

The Chicago Cubs take on the St. Louis Cardinals in the rubber match of a tightly contested series, with both teams fighting for critical NL Central positioning. Power hitting and strong starting pitching could be decisive factors, and the ideal weather conditions set the stage for a thrilling showdown at Busch Stadium. Fans can expect an entertaining matchup with playoff implications as both teams look to gain momentum heading into the season's final stretch.

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