Milwaukee Brewers vs. St. Louis Cardinals: Game Preview, Odds, and Key Players for September 20, 2025

Saturday, September 20th, 2025

Milwaukee Brewers vs. St. Louis Cardinals: Key NL Central Clash at Busch Stadium

Game Overview

The Milwaukee Brewers (94-60, first in the NL Central) travel to face the St. Louis Cardinals (75-79, fourth in the NL Central) at Busch Stadium in a significant late-season matchup. The game is set for 6:15 PM local time, with both teams aiming to make a statement as the regular season winds down. With the Brewers fighting to maintain their lead atop the division and the Cardinals seeking a strong finish at home, this contest offers high stakes and plenty of intrigue.

Pitching Probables

The Brewers send Chad Patrick (3-8, 3.64 ERA, 1.28 WHIP, 116 strikeouts) to the mound, aiming to snap Milwaukee’s four-game road skid. Opposing him will be Miles Mikolas (8-10, 4.80 ERA, 1.31 WHIP, 93 strikeouts) for the Cardinals. Oddsmakers give the Brewers a slight edge at -124, with the Cardinals at +104. The over/under is set at 7.5 runs, reflecting expectations for a balanced game.

Weather

At Busch Stadium today, expect mostly sunny skies with a high near 77°F, perfect conditions for baseball. There's little chance of precipitation, so rain delays are unlikely. Winds will be light out of the southwest at around 6 mph, having minimal impact on fly balls and gameplay.

Recent Performance

The Cardinals enter this matchup at 75-79 overall and 43-36 at home. Notably, St. Louis holds an impressive 38-18 record in games where they do not allow a home run, demonstrating their ability to limit power at Busch Stadium.

The Brewers own a 43-33 road record, sitting at 94-60 overall. They have excelled when generating offense, with a remarkable 67-14 mark in games where they out-hit opponents. This matchup marks the 12th meeting between these rivals this season, with the Brewers holding a narrow 6-5 edge in the season series.

Top Performers to Watch

For the Cardinals, Alec Burleson leads the team with a .289 batting average, 25 doubles, two triples, and 18 home runs. Thomas Saggese has heated up recently, hitting 14-for-37 with one home run and six RBI over the past 10 games.

On the Brewers’ side, Christian Yelich continues to anchor the lineup with 29 home runs and a slugging percentage of .466. Jake Bauers is another key contributor, going 12-for-27 with two home runs and six RBI in his last 10 games.

Last 10 Games

The Cardinals face a bit of adversity, going 3-7 in their last 10 games with a .240 team batting average and a 4.20 ERA, being outscored by 12 runs along the way.

The Brewers are 5-5 over their last 10, boasting a strong .285 batting average and a 4.03 ERA, outscoring opponents by eight runs during that stretch.

Injuries

The Cardinals are missing several key players, including Willson Contreras (10-Day IL, shoulder), Masyn Winn (10-Day IL, meniscus), and Zack Thompson (60-Day IL, lat).

The Brewers’ list includes Jose Quintana (15-Day IL, calf), Shelby Miller (60-Day IL, elbow), Logan Henderson (60-Day IL, elbow), Trevor Megill (15-Day IL, flexor strain), D.L. Hall (15-Day IL, oblique), Jordan Montgomery (60-Day IL, elbow), Garrett Mitchell (60-Day IL, oblique), and Connor Thomas (60-Day IL, elbow).

In Summary

The Milwaukee Brewers and St. Louis Cardinals renew their NL Central rivalry at Busch Stadium with both teams determined to improve their recent fortunes. With ideal weather, solid pitching probables, and key hitters to watch, fans can expect an exciting and competitive showdown. The Brewers look to snap their road skid and extend their season series lead, while the Cardinals aim to leverage home-field advantage and finish the year strong. Stay tuned for updates and analysis as these division foes battle it out in St. Louis.

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