San Diego Padres at Milwaukee Brewers MLB Game Preview (June 6, 2025)

Friday, June 6th, 2025

The Milwaukee Brewers host the San Diego Padres on Friday to begin a three-game series.

Matchup Details

San Diego Padres (35-26, second in NL West) at Milwaukee Brewers (34-29, third in NL Central)

Date: June 6, 2025

Time: 7:10 PM CT

Location: Milwaukee

Pitching Matchup

Padres: Randy Vasquez (3-4, 3.99 ERA, 1.47 WHIP, 35 strikeouts)

Brewers: Chad Patrick (3-4, 2.97 ERA, 1.21 WHIP, 57 strikeouts)

Odds

Brewers -147, Padres +124; over/under is 8 1/2 runs

Team Form

Milwaukee is 34-29 overall and 18-10 at home. The Brewers have the seventh-ranked team ERA in the NL at 3.92.

San Diego has gone 15-16 on the road and 35-26 overall. The Padres are 25-7 in games when they out-hit their opponents.

Friday's game is the first time these teams square off this season.

Top Performers

For the Brewers, Jackson Chourio has 10 home runs, nine walks and 37 RBI while hitting .260. Christian Yelich is 17 for 42 with a double, four home runs and 11 RBI over the last 10 games.

For the Padres, Manny Machado has 17 doubles, eight home runs and 31 RBI. Jackson Merrill is 9 for 39 with four doubles, a home run and five RBI over the last 10 games.

Last 10 Games

Brewers: 9-1, .268 batting average, 2.97 ERA, outscored opponents by 31 runs

Padres: 6-4, .226 batting average, 3.72 ERA, outscored by one run

Injuries

Brewers: Connor Thomas: 60-Day IL (elbow), Blake Perkins: 60-Day IL (shin), Garrett Mitchell: 10-Day IL (oblique), Nestor Cortes: 60-Day IL (elbow), Brandon Woodruff: 15-Day IL (shoulder), Robert Gasser: 60-Day IL (elbow)

Padres: Luis Arraez: day-to-day (knee), Xander Bogaerts: day-to-day (shoulder), Michael King: 15-Day IL (shoulder), Jason Heyward: 10-Day IL (oblique), Mason McCoy: 10-Day IL (finger), Bryan Hoeing: 60-Day IL (shoulder), Logan Gillaspie: 15-Day IL (oblique), Jhony Brito: 60-Day IL (forearm), Yu Darvish: 15-Day IL (elbow), Joe Musgrove: 60-Day IL (elbow)

In summary

The San Diego Padres face the Milwaukee Brewers on June 6, 2025, at 7:10 PM CT in Milwaukee. The Padres hold a 35-26 record, while the Brewers are 34-29. Randy Vasquez is scheduled to pitch for San Diego against Chad Patrick for Milwaukee. The Brewers are favored in this matchup with an over/under of 8 1/2 runs. Milwaukee has performed well recently, going 9-1 in their last 10 games, compared to San Diego's 6-4 record. Jackson Chourio and Christian Yelich are key hitters for the Brewers, while Manny Machado and Jackson Merrill lead the Padres' offense. Both teams are dealing with significant injury lists.

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