Friday, July 4th, 2025

The St. Louis Cardinals face the Chicago Cubs on July 4, 2025, at 1:20 PM CT in Chicago.
The St. Louis Cardinals (47-41, third in NL Central) visit the Chicago Cubs (52-35, first in NL Central).
Location: Chicago
Date: Friday, July 4, 2025
Time: 1:20 PM CT (2:20 PM EDT)
Cardinals Probable Pitcher: Miles Mikolas (4-5, 4.76 ERA, 1.32 WHIP, 56 strikeouts)
Cubs Probable Pitcher: Colin Rea (5-3, 4.37 ERA, 1.37 WHIP, 56 strikeouts)
Cubs: -157
Cardinals: +131
Over/Under: 10 runs
The St. Louis Cardinals come into this matchup against the Chicago Cubs having lost three games in a row.
Chicago holds a 52-35 overall record, including a strong 28-15 record at home. Cubs hitters collectively bat .255, ranking third in the National League.
St. Louis has a 47-41 overall record and is 21-24 on the road. The Cardinals pitching staff ranks 10th in the NL with a team ERA of 3.94.
This marks the fifth meeting between these division rivals this season, with the series currently tied at two wins apiece.
For the Cubs, Seiya Suzuki has been a key contributor with 20 doubles, three triples, and 23 home runs. Nico Hoerner has been productive over the last 10 games, going 10 for 34 with three home runs.
Willson Contreras leads the Cardinals with 19 doubles, 11 home runs, and 51 RBI. Nolan Gorman has hit well recently, going 9 for 38 with three home runs in the last 10 games.
Over their last 10 games, the Cubs have gone 6-4 with a .262 batting average and a 3.41 ERA, outscoring opponents by 13 runs.
The Cardinals have a 5-5 record in their last 10 games, posting a .234 batting average and a 4.03 ERA, being outscored by two runs.
Cubs Injuries: Miguel Amaya (oblique), Eli Morgan (elbow), Javier Assad (oblique), Justin Steele (elbow)
Cardinals Injuries: Nolan Arenado (finger), Willson Contreras (hand), Jordan Walker (appendicitis), Ivan Herrera (hamstring), Zack Thompson (lat)
The Chicago Cubs (52-35) host the St. Louis Cardinals (47-41) on July 4, 2025, at 1:20 PM CT. The Cubs, leading the season series 2-2, send Colin Rea (5-3, 4.37 ERA) to the mound against the Cardinals' Miles Mikolas (4-5, 4.76 ERA). Chicago is favored in the matchup with a strong home record and better recent form. Both teams have key players dealing with injuries ahead of this division clash.
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