Astros at Pirates Game Preview: June 4, 2025

Wednesday, June 4th, 2025

Houston Astros vs. Pittsburgh Pirates MLB Preview - June 4, 2025

The Houston Astros (33-27, first in the AL West) are set to face the Pittsburgh Pirates (22-39, fifth in the NL Central) on Wednesday, June 4, 2025. The game is scheduled for 6:40 p.m. EDT in Pittsburgh.

Pitching Matchup and Odds

The pitching matchup features Ryan Gusto (3-2, 4.62 ERA, 1.56 WHIP, 42 strikeouts) for the Astros against Mike Burrows (0-1, 8.64 ERA, 1.56 WHIP, five strikeouts) for the Pirates.

The Astros are the favorites at -140 on the moneyline, while the Pirates are underdogs at +118. The over/under for total runs is set at 9.

Series Status and Team Insights

Houston holds a 1-0 lead in the current series against Pittsburgh. This marks the second meeting between the two teams this season.

Pittsburgh Pirates

The Pirates hold a 22-39 overall record and a 13-17 record when playing at home. Pittsburgh has performed well when scoring, boasting a 9-3 record in games where they tally five or more runs.

Houston Astros

Houston's overall record stands at 33-27, including an 11-15 record in road games. The Astros have demonstrated power at the plate, with a 12-4 record in games where they hit two or more home runs.

Key Player Performance

Pirates Top Performers

Oneil Cruz leads the Pirates with 12 home runs and holds a .468 slugging percentage. Andrew McCutchen has been notable over the past 10 games, going 12 for 38 with two home runs and four RBI.

Astros Top Performers

Jeremy Pena leads the Astros with a .308 batting average, accumulating nine doubles, a triple, and nine home runs. Jose Altuve has been hot over the last 10 games, batting 14 for 39 with three home runs and four RBI.

Recent Performance

Pirates Last 10 Games

In their last 10 games, the Pirates have a 5-5 record. They have a .262 batting average and a 3.38 ERA, outscoring their opponents by seven runs in this span.

Astros Last 10 Games

The Astros have a 7-3 record over their last 10 games. They are batting .266 with a 4.30 ERA, being outscored by five runs in this recent stretch.

Injury Report

Pirates Injuries

Joey Bart: 7-Day IL (concussion), Colin Holderman: 15-Day IL (thumb), Enmanuel Valdez: 60-Day IL (shoulder), Justin Lawrence: 60-Day IL (elbow), Tim Mayza: 60-Day IL (shoulder), Jared Jones: 60-Day IL (elbow), Johan Oviedo: 60-Day IL (elbow), Dauri Moreta: 60-Day IL (elbow).

Astros Injuries

Chas McCormick: 10-Day IL (oblique), Ronel Blanco: 60-Day IL (elbow), Zach Dezenzo: 10-Day IL (hand), Hayden Wesneski: 60-Day IL (elbow), Yordan Alvarez: 10-Day IL (hand), Spencer Arrighetti: 15-Day IL (thumb), Luis Garcia: 60-Day IL (elbow), Cristian Javier: 60-Day IL (elbow), J.P. France: 60-Day IL (shoulder), Taylor Trammell: 10-Day IL (calf), Pedro Leon: 10-Day IL (knee).

In summary

The Houston Astros face the Pittsburgh Pirates in Pittsburgh on June 4, 2025, holding a 1-0 series lead. The Astros, first in the AL West, have a 33-27 record and are favored with Ryan Gusto pitching. The Pirates, fifth in the NL Central, have a 22-39 record and will start Mike Burrows. Houston performs well when hitting home runs, while Pittsburgh finds success when scoring five or more runs. Key players include Oneil Cruz and Andrew McCutchen for the Pirates, and Jeremy Pena and Jose Altuve for the Astros. Both teams have several players on the injured list entering the contest.

Related Links

• Houston Astros News & Updates
• Houston Astros Schedule & Scores
• Pittsburgh Pirates News & Updates
• Pittsburgh Pirates Schedule & Scores
• MLB News