Chicago White Sox vs. Washington Nationals: Game Preview, Odds, Pitching Matchup for September 27, 2025

Saturday, September 27th, 2025

Chicago White Sox Take on Washington Nationals at Nationals Park

The Chicago White Sox (59-101, fifth in the AL Central) travel to face the Washington Nationals (65-95, fifth in the NL East) at Nationals Park on Saturday at 4:05 p.m. EDT.

Pitching Matchup

The White Sox are set to start Sean Burke (4-11, 4.29 ERA, 1.47 WHIP, 123 strikeouts), while the Nationals will counter with Jake Irvin (9-13, 5.69 ERA, 1.44 WHIP, 118 strikeouts). Oddsmakers have the Nationals as slight favorites at -120, with the White Sox at +100 and the over/under set at 8 1/2 runs.

Weather

At Nationals Park today, expect pleasant baseball weather with a high near 76°F under mostly sunny skies. There is little to no chance of precipitation, and winds will be light out of the southwest at 6-10 mph, providing ideal conditions for players and fans alike.

Team Breakdown

Washington enters play with an overall record of 65-95 and a 31-48 mark at home. The Nationals have clubbed 158 home runs, ranking 10th in the National League. Chicago is 59-101 overall and 26-53 on the road. The White Sox have struggled in close games, posting a 15-35 record in games decided by one run.

This game marks the second meeting between these two teams this season.

Standout Performers

For the Nationals, Luis Garcia leads the way with 28 doubles, a triple, 16 home runs, and 66 RBIs. Daylen Lile has impressed recently, going 14-for-37 with a double, two triples, and three home runs over his last 10 games.

The White Sox have benefited from the play of Chase Meidroth, who boasts 15 doubles, five home runs, and 23 RBIs. Rookie Colson Montgomery is 11-for-38 with two doubles and two home runs in his last 10 games.

Recent Form

The Nationals have struggled recently, going 3-7 over their last 10 games with a .234 team batting average and a 5.60 ERA, being outscored by 23 runs. The White Sox are 2-8 in their last 10, managing a .197 batting average and a 5.37 ERA, while being outscored by 19 runs.

Injury Report

The Nationals’ injury list includes Mason Thompson (biceps), MacKenzie Gore (ankle), Cole Henry (back), Drew Millas (finger), Trevor Williams (elbow), Keibert Ruiz (concussion), Derek Law (forearm), DJ Herz (elbow), and Josiah Gray (elbow).

For the White Sox, missing players include Mike Tauchman (knee), Wikelman Gonzalez (elbow), Andrew Benintendi (achilles), Martin Perez (shoulder), Bryan Hudson (back), Luis Robert (hamstring), Elvis Peguero (elbow), Prelander Berroa (elbow), Ky Bush (elbow), Miguel Castro (knee), and Drew Thorpe (elbow).

In summary

The Chicago White Sox face off against the Washington Nationals at Nationals Park in an end-of-season matchup between two rebuilding teams. With promising young talent on both sides and nearly ideal weather conditions anticipated, Saturday’s game is an opportunity for players to shine and finish the season strong. Fans can expect an afternoon of competitive baseball and potentially high-scoring action, given the recent struggles by both pitching staffs.

MLB Schedules

Today's MLB Games

There are no baseball games today.

Tomorrow's MLB Games

There are no baseball games tomorrow.

Yesterday's MLB Games

There were no baseball games yesterday.