Detroit Tigers vs. Pittsburgh Pirates Game Preview: July 22, 2025 MLB

Tuesday, July 22nd, 2025

Detroit Tigers at Pittsburgh Pirates Game Preview: July 22, 2025

The Detroit Tigers (60-41, first in the AL Central) are set to face the Pittsburgh Pirates (40-61, fifth in the NL Central) on Tuesday, July 22, 2025, at PNC Park in Pittsburgh. First pitch is scheduled for 5:40 PM EDT.

Pitching Probables

For the Tigers, Casey Mize (9-3) is slated to start. He holds a 3.15 ERA, 1.22 WHIP, and has recorded 77 strikeouts. The Pirates will counter with Mitch Keller (3-10), who carries a 3.48 ERA, 1.14 WHIP, and 92 strikeouts.

Betting Information

The Tigers are favored in this matchup with odds of -150, while the Pirates are the underdog at +126. The over/under for total runs in the game is set at 8.

Key Matchup Insights

The Pittsburgh Pirates will host the Detroit Tigers, leading the current series 1-0. Pittsburgh has a home record of 27-24 and an overall record of 40-61. They've been effective when their offense clicks, holding a 28-17 record in games where they register eight or more hits.

Detroit comes into this game with a strong 60-41 overall record, including a 28-23 mark in road games. The Tigers have shown a tendency to win convincingly when they score, boasting a 41-6 record in games where they put up five or more runs.

This will be the fifth meeting between these two teams this season, with the overall season series currently tied at 2-2.

Top Performers

For the Pirates, Andrew McCutchen has been a consistent offensive threat, with 15 doubles, eight home runs, and 31 RBI, maintaining a .256 batting average. Tommy Pham has been hot over the last 10 games, going 11 for 35 with two doubles and two home runs.

Leading the Tigers' offense, Gleyber Torres has nine home runs, 54 walks, and 45 RBI, hitting .281. Colt Keith has also contributed recently, with 8 hits in 31 at-bats, including two doubles, two home runs, and four RBI over the past 10 games.

Recent Performance

Both teams have struggled in their last 10 games. The Pirates hold a 2-8 record, batting .220 with a 6.13 ERA, and have been outscored by 33 runs.

The Tigers are not faring much better, with a 3-7 record in their last 10 outings. They have a .209 batting average, a 5.48 ERA, and have been outscored by 26 runs.

Injury Report

Pirates: Chase Shugart (knee, 15-Day IL), Ryan Borucki (back, 15-Day IL), Endy Rodriguez (elbow, 60-Day IL), Enmanuel Valdez (shoulder, 60-Day IL), Justin Lawrence (elbow, 60-Day IL), Tim Mayza (shoulder, 60-Day IL), Jared Jones (elbow, 60-Day IL), Johan Oviedo (elbow, 60-Day IL).

Tigers: Sean Guenther (hip, 60-Day IL), Sawyer Gipson-Long (neck, 15-Day IL), Kerry Carpenter (hamstring, 10-Day IL), Jackson Jobe (flexor, 60-Day IL), Jason Foley (shoulder, 60-Day IL), Alex Cobb (hip, 60-Day IL), Ty Madden (shoulder, 60-Day IL), Jose Urquidy (elbow, 60-Day IL), Alex Lange (lat, 60-Day IL).

In summary

The Detroit Tigers (60-41) visit the Pittsburgh Pirates (40-61) on July 22, 2025, at 5:40 PM EDT. Detroit, leading the AL Central, sends Casey Mize (9-3, 3.15 ERA) to the mound against Pittsburgh's Mitch Keller (3-10, 3.48 ERA). The Tigers are favored at -150, with the over/under at 8 runs. The Pirates currently lead the immediate series 1-0, though the season series is tied 2-2. Both teams are struggling recently, with the Pirates 2-8 and the Tigers 3-7 in their last 10 games. Key performers include Andrew McCutchen and Tommy Pham for Pittsburgh, and Gleyber Torres and Colt Keith for Detroit. Multiple players are on the injured list for both clubs.

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