Houston Astros at Cleveland Guardians Preview: June 6, 2025

Friday, June 6th, 2025

The Cleveland Guardians host the Houston Astros to begin a three-game series.

The Astros come into the matchup with a 34-28 record, good for first place in the AL West. They have a 12-16 record in road games. The Astros rank 10th in the AL with 63 total home runs, averaging one per game.

The Guardians are 33-28 overall and 17-11 at home. Cleveland's hitters have a collective .305 on-base percentage, ranking 10th in the AL.

This is the first meeting of the season between the two clubs. The Guardians are -112 favorites in the game, according to oddsmakers, and the over/under is 8 1/2 runs.

PITCHING PROBABLES

Astros: Colton Gordon (0-1, 5.95 ERA, 1.37 WHIP, 20 strikeouts)

Guardians: Logan Allen (3-3, 4.22 ERA, 1.59 WHIP, 38 strikeouts)

TOP PERFORMERS

Jose Ramirez leads the Guardians with a .330 batting average. He has 14 doubles, a triple, and 11 home runs. Carlos Santana is 14 for 37 with a home run and three RBI over the past 10 games.

Isaac Paredes leads the Astros with 14 home runs and a .474 slugging percentage. Jeremy Pena is 17 for 40 with three home runs and six RBI over the past 10 games.

LAST 10 GAMES

Guardians: 4-6, .231 batting average, 4.14 ERA, outscored by 11 runs

Astros: 7-3, .251 batting average, 4.25 ERA, outscored by one run

INJURIES

Guardians:

Andrew Walters: 15-Day IL (Lat)

Lane Thomas: 10-Day IL (Foot)

Ben Lively: 60-Day IL (Forearm)

Will Brennan: 10-Day IL (Forearm)

Paul Sewald: 15-Day IL (Shoulder)

Shane Bieber: 60-Day IL (Elbow)

Erik Sabrowski: 60-Day IL (Elbow)

Trevor Stephan: 60-Day IL (Elbow)

John Means: 60-Day IL (Elbow)

Sam Hentges: 60-Day IL (Shoulder)

Astros:

Chas McCormick: 10-Day IL (Oblique)

Ronel Blanco: 60-Day IL (Elbow)

Zach Dezenzo: 10-Day IL (Hand)

Hayden Wesneski: 60-Day IL (Elbow)

Yordan Alvarez: 10-Day IL (Hand)

Spencer Arrighetti: 15-Day IL (Thumb)

Luis Garcia: 60-Day IL (Elbow)

Cristian Javier: 60-Day IL (Elbow)

J.P. France: 60-Day IL (Shoulder)

Taylor Trammell: 10-Day IL (Calf)

Pedro Leon: 10-Day IL (Knee)

In summary

The Houston Astros (34-28) visit the Cleveland Guardians (33-28) to open a three-game series. Houston leads the AL West, while Cleveland is third in the AL Central. The pitching matchup features Colton Gordon for the Astros and Logan Allen for the Guardians. Cleveland has a slight edge in the odds. Key performers include Jose Ramirez for Cleveland and Isaac Paredes for Houston. The Astros are coming off a strong 7-3 run in their last 10 games, while the Guardians are 4-6 in the same span. Both teams have several players on the injured list.

Related Links

• Houston Astros News & Updates
• Houston Astros Schedule & Scores
• Cleveland Guardians News & Updates
• Cleveland Guardians Schedule & Scores
• MLB News