MLB Game Preview: Chicago Cubs at Houston Astros (June 27, 2025)

Friday, June 27th, 2025

The Houston Astros are set to host the Chicago Cubs on June 27, 2025, for the start of a three-game series at home.

Matchup Details

The game is scheduled for Friday, June 27, 2025, in Houston at 7:10 PM CT (8:10 PM EDT).

Both teams enter the series with identical 48-33 records. The Chicago Cubs are currently first in the NL Central, while the Houston Astros lead the AL West.

Pitching Probables

The Cubs are expected to send Cade Horton to the mound. Horton holds a 3-1 record with a 3.73 ERA, a 1.29 WHIP, and 31 strikeouts.

For the Astros, Brandon Walter is the projected starter. Walter has a 0-1 record, a 3.80 ERA, a 1.10 WHIP, and 25 strikeouts.

Betting Odds

According to oddsmakers, the Astros are slight favorites at -112, with the Cubs listed at -107. The over/under for total runs scored in the game is set at 8 1/2.

Team Analysis

Houston boasts a strong home record this season, going 30-13 at Minute Maid Park. Their pitching staff has been effective, ranking second in the AL with a collective 3.41 ERA.

Chicago comes into the series with a solid road record of 23-18. The Cubs' offense has been productive, with their .325 collective on-base percentage ranking fifth across MLB.

This game marks the first meeting between the Cubs and Astros this season.

Top Performers

For the Astros, Isaac Paredes is a key offensive threat, leading the team with 16 home runs and slugging .463. Mauricio Dubon has been hot recently, hitting 10 for 34 with four home runs and six RBI over his last 10 contests.

Kyle Tucker has been a standout for the Cubs, hitting .287 with 16 home runs, 53 walks, and 49 RBI. Michael Busch is also in good form, going 12 for 37 with a double, two home runs, and seven RBI in his last 10 games.

Last 10 Games

The Astros have been playing well, posting a 7-3 record over their last 10 games. During this stretch, they've hit .270 with a 3.23 ERA, outscoring their opponents by 11 runs.

The Cubs are 5-5 in their last 10 games. Their offense has hit .257, but their pitching has struggled with a 5.66 ERA, resulting in them being outscored by four runs.

Injuries

Houston's injured list includes Jacob Melton (ankle), Shawn Dubin (forearm), Pedro Leon (knee), Brendan Rodgers (oblique), Lance McCullers (foot), Spencer Arrighetti (thumb), Chas McCormick (oblique), Ronel Blanco (elbow), Zach Dezenzo (hand), Hayden Wesneski (elbow), Yordan Alvarez (hand), Luis Garcia (elbow), Cristian Javier (elbow), and J.P. France (shoulder).

The Cubs are dealing with injuries to Miguel Amaya (oblique), Eli Morgan (elbow), Javier Assad (oblique), and Justin Steele (elbow).

In summary

The Chicago Cubs (48-33) face the Houston Astros (48-33) in Houston on June 27, 2025. Both teams are in first place in their respective divisions. The game features a pitching matchup between the Cubs' Cade Horton (3-1, 3.73 ERA) and the Astros' Brandon Walter (0-1, 3.80 ERA). Houston is a slight favorite, and the over/under is 8.5 runs. This is the first meeting between the two clubs this season. Key players to watch include Isaac Paredes and Mauricio Dubon for the Astros, and Kyle Tucker and Michael Busch for the Cubs. Both teams have several players on the injured list.

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