MLB Games on Wednesday, May 4, 1921
5 games on Wednesday, May 4, 1921. Start times are Eastern Time.
| Matchup | Status | Details |
|---|---|---|
| Brooklyn Robins 2 at New York Giants 3 | Final | Game page: Brooklyn Robins at New York Giants, Wed, May 4, 1921 |
 Philadelphia Phillies
2
at Boston Braves
5
|
Final | Game page: Philadelphia Phillies at Boston Braves, Wed, May 4, 1921 |
| Indianapolis ABC's 2 at Cincinnati Cuban Stars 7 | Final | Game page: Indianapolis ABC's at Cincinnati Cuban Stars, Wed, May 4, 1921 |
 Chicago White Sox
8
 at Detroit Tigers
11
|
Final | Game page: Chicago White Sox at Detroit Tigers, Wed, May 4, 1921 |
 Cincinnati Reds
1
 at Chicago Cubs
3
|
Final | Game page: Cincinnati Reds at Chicago Cubs, Wed, May 4, 1921 |