MLB Games on Saturday, October 22, 2022
2 games on Saturday, October 22, 2022. Start times are Eastern Time.
| Matchup | Status | Details |
|---|---|---|
 Houston Astros
5
 at New York Yankees
0
|
Final Postseason | Game page: Houston Astros at New York Yankees, Sat, Oct 22, 2022 |
 San Diego Padres
6
 at Philadelphia Phillies
10
|
Final Postseason | Game page: San Diego Padres at Philadelphia Phillies, Sat, Oct 22, 2022 |