Houston Astros vs Oakland Athletics: Preview, Odds & Pitching Matchup for September 24, 2025 Showdown

Wednesday, September 24th, 2025

Houston Astros vs. Oakland Athletics: September 24, 2025 MLB Preview

The Houston Astros, currently second in the AL West with an 84-73 record, look to halt a four-game losing streak as they face the Oakland Athletics, who stand fourth in the division at 74-83. The game takes place in West Sacramento, California, with the first pitch scheduled for 10:05 p.m. EDT.

Pitching Matchup

The Astros will send Hunter Brown to the mound. Brown boasts a strong season with a 12-8 record, 2.30 ERA, 1.01 WHIP, and 201 strikeouts. The Athletics counter with Luis Severino, who enters with a 7-11 record, 4.72 ERA, 1.33 WHIP, and 119 strikeouts.

Team Performance Overview

The Athletics have played to a 74-83 record overall, with a 34-42 mark at home. Offensively, the team maintains a .253 batting average, ranking fifth in Major League Baseball. On the other side, Houston comes into the contest at 84-73 overall and an even 38-38 on the road. The Astros have excelled when out-hitting their opponents, going 62-21 in such games.

Season Series

This matchup marks the 12th meeting between the Astros and Athletics this season. Oakland currently holds a 7-4 edge in the season series, adding extra intrigue to this late-season contest.

Players to Watch

For the Athletics, Tyler Soderstrom has been a force at the plate, recording 32 doubles, one triple, 24 home runs, and 91 RBIs while batting .278. Jacob Wilson is heating up, notching 11 hits in his last 36 at-bats with four doubles and one home run over the past 10 games.

The Astros rely on Jeremy Pena who leads the team with a .304 average, 30 doubles, two triples, 17 home runs, 35 walks, and 62 RBIs. Yordan Alvarez is 10 for 33 with a homer and two RBIs in his last 10 games.

Recent Form

The Athletics have gone 7-3 in their last 10 games, posting a .233 batting average and a 2.96 ERA, outscoring their opponents by six runs. The Astros are 5-5 over their last 10, matching the .233 average but with a 4.30 ERA and an even run differential.

Injury Report

Athletics: Sean Newcomb (elbow), Zack Gelof (shoulder), Ben Bowden (lat), Joey Estes (back), Jacob Lopez (flexor), Jack Perkins (shoulder), Austin Wynns (abdomen), Denzel Clarke (abductor), Grant Holman (shoulder), Gunnar Hoglund (hip), Jose Leclerc (shoulder), Luis Medina (elbow) are on IL.

Astros: Jeremy Pena (oblique), Kaleb Ort (elbow), Yordan Alvarez (ankle), Lance McCullers (hand), Luis Garcia (elbow), Spencer Arrighetti (elbow), John Rooney (concussion/nasal), Brendan Rodgers (oblique), Pedro Leon (knee), Brandon Walter (elbow), Bennett Sousa (elbow), Josh Hader (shoulder), Zach Dezenzo (hand), Ronel Blanco (elbow), Hayden Wesneski (elbow) are also sidelined.

In summary

The Houston Astros aim to snap a four-game slide as they challenge the Oakland Athletics, who lead the season series. Hunter Brown’s standout pitching and Jeremy Pena’s steady bat highlight Houston's strengths, while Luis Severino and Tyler Soderstrom anchor Oakland's effort. As both clubs navigate key injuries and the season winds down, this AL West matchup promises competitive action and playoff implications.

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