MLB Games on Wednesday, April 18, 1906
7 games on Wednesday, April 18, 1906. Start times are Eastern Time.
| Matchup | Status | Details |
|---|---|---|
 Cincinnati Reds
7
 at Pittsburgh Pirates
4
|
Final | Game page: Cincinnati Reds at Pittsburgh Pirates, Wed, Apr 18, 1906 |
| New York Giants 4 at Brooklyn Superbas 1 | Final | Game page: New York Giants at Brooklyn Superbas, Wed, Apr 18, 1906 |
| New York Highlanders 3 at Boston Americans 3 | Final (11) | Game page: New York Highlanders at Boston Americans, Wed, Apr 18, 1906 |
| Washington Senators 2 at Philadelphia Athletics 4 | Final | Game page: Washington Senators at Philadelphia Athletics, Wed, Apr 18, 1906 |
 Chicago White Sox
2
 at Detroit Tigers
3
|
Final | Game page: Chicago White Sox at Detroit Tigers, Wed, Apr 18, 1906 |
| Cleveland Naps 4 at St. Louis Browns 0 | Final | Game page: Cleveland Naps at St. Louis Browns, Wed, Apr 18, 1906 |
 St. Louis Cardinals
1
 at Chicago Cubs
11
|
Final | Game page: St. Louis Cardinals at Chicago Cubs, Wed, Apr 18, 1906 |