MLB Games on Wednesday, September 7, 1921
8 games on Wednesday, September 7, 1921. Start times are Eastern Time.
| Matchup | Status | Details |
|---|---|---|
 Boston Red Sox
2
 at New York Yankees
6
|
Final | Game page: Boston Red Sox at New York Yankees, Wed, Sep 7, 1921 |
 Detroit Tigers
4
at Cleveland Indians
5
|
Final | Game page: Detroit Tigers at Cleveland Indians, Wed, Sep 7, 1921 |
New York Giants
7
 at Philadelphia Phillies
2
|
Final | Game page: New York Giants at Philadelphia Phillies, Wed, Sep 7, 1921 |
| Chicago American Giants 5 at Kansas City Monarchs 4 | Final | Game page: Chicago American Giants at Kansas City Monarchs, Wed, Sep 7, 1921 |
|
Boston Red Sox
2
at New York Yankees
7
|
Final | Game page: Boston Red Sox at New York Yankees, Wed, Sep 7, 1921 |
|
New York Giants
13
at Philadelphia Phillies
4
|
Final | Game page: New York Giants at Philadelphia Phillies, Wed, Sep 7, 1921 |
 Chicago White Sox
2
at St. Louis Browns
10
|
Final | Game page: Chicago White Sox at St. Louis Browns, Wed, Sep 7, 1921 |
 Cincinnati Reds
5
 at Chicago Cubs
2
|
Final (10) | Game page: Cincinnati Reds at Chicago Cubs, Wed, Sep 7, 1921 |