MLB Games on Tuesday, September 22, 1925
8 games on Tuesday, September 22, 1925. Start times are Eastern Time.
| Matchup | Status | Details |
|---|---|---|
 Chicago White Sox
6
 at New York Yankees
11
|
Final | Game page: Chicago White Sox at New York Yankees, Tue, Sep 22, 1925 |
| Cleveland Indians 2 at Washington Senators 3 | Final | Game page: Cleveland Indians at Washington Senators, Tue, Sep 22, 1925 |
 Detroit Tigers
11
 at Boston Red Sox
8
|
Final | Game page: Detroit Tigers at Boston Red Sox, Tue, Sep 22, 1925 |
 Philadelphia Phillies
4
 at Pittsburgh Pirates
14
|
Final | Game page: Philadelphia Phillies at Pittsburgh Pirates, Tue, Sep 22, 1925 |
| St. Louis Browns 1 at Philadelphia Athletics 0 | Final | Game page: St. Louis Browns at Philadelphia Athletics, Tue, Sep 22, 1925 |
|
Chicago White Sox
4
at New York Yankees
2
|
Final | Game page: Chicago White Sox at New York Yankees, Tue, Sep 22, 1925 |
|
Detroit Tigers
7
at Boston Red Sox
2
|
Final | Game page: Detroit Tigers at Boston Red Sox, Tue, Sep 22, 1925 |
Brooklyn Robins
2
 at Chicago Cubs
3
|
Final (12) | Game page: Brooklyn Robins at Chicago Cubs, Tue, Sep 22, 1925 |