San Francisco Giants at San Diego Padres
Final score
The San Diego Padres beat the San Francisco Giants 8–4 on Thursday, August 21, 2025 at home.
| Team | Runs | 2025 record |
|---|---|---|
 San Francisco Giants |
4 | 81-81 |
 at San Diego Padres |
8 | 90-72 |
News about this game
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Padres Crush Giants 8-1: Gavin Sheets Homers Twice, Fernando Tatis Jr. Robs Devers in San Diego Showdown (Aug. 20, 2025)
Gavin Sheets powered the Padres with two homers and four RBIs, while Fernando Tatis Jr. robbed Rafael Devers of a home run as San Diego cruised past the San Francisco Giants 8-1 on August 20, 2025, thrilling fans with key plays and closing the NL West gap.
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San Francisco Giants vs. San Diego Padres: Verlander Faces Cease in NL West Showdown – August 21, 2025
Get the latest matchup preview as the San Diego Padres, led by Manny Machado, host the San Francisco Giants with veteran ace Justin Verlander on the mound. See key stats, pitching probables, injuries, and top performers for their August 21, 2025 NL West clash.
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Manny Machado Powers San Diego Padres Past San Francisco Giants 8-4 in NL West Clash (August 21, 2025)
Manny Machado powered the Padres with three RBIs as San Diego defeated the Giants 8-4 on August 21, 2025, taking the series and building momentum for their crucial NL West battle against the Dodgers. Get all the key highlights and stats from this action-packed MLB matchup.
2025 season series
Other MLB games on Aug 21
| Matchup | Status | Details |
|---|---|---|
 Athletics
8
 at Minnesota Twins
3
|
Final | Game page: Athletics at Minnesota Twins, Thu, Aug 21, 2025 |
 Texas Rangers
4
 at Kansas City Royals
6
|
Final | Game page: Texas Rangers at Kansas City Royals, Thu, Aug 21, 2025 |
 Milwaukee Brewers
4
 at Chicago Cubs
1
|
Final | Game page: Milwaukee Brewers at Chicago Cubs, Thu, Aug 21, 2025 |
 Los Angeles Dodgers
9
 at Colorado Rockies
5
|
Final | Game page: Los Angeles Dodgers at Colorado Rockies, Thu, Aug 21, 2025 |
 New York Mets
3
 at Washington Nationals
9
|
Final | Game page: New York Mets at Washington Nationals, Thu, Aug 21, 2025 |
 Boston Red Sox
6
 at New York Yankees
3
|
Final | Game page: Boston Red Sox at New York Yankees, Thu, Aug 21, 2025 |
 Houston Astros
7
 at Baltimore Orioles
2
|
Final | Game page: Houston Astros at Baltimore Orioles, Thu, Aug 21, 2025 |
 St. Louis Cardinals
7
 at Tampa Bay Rays
4
|
Final | Game page: St. Louis Cardinals at Tampa Bay Rays, Thu, Aug 21, 2025 |