MLB Games on Thursday, September 22, 1921
7 games on Thursday, September 22, 1921. Start times are Eastern Time.
| Matchup | Status | Details |
|---|---|---|
Brooklyn Robins
1
 at Pittsburgh Pirates
3
|
Final | Game page: Brooklyn Robins at Pittsburgh Pirates, Thu, Sep 22, 1921 |
Cleveland Indians
9
 at Boston Red Sox
8
|
Final (12) | Game page: Cleveland Indians at Boston Red Sox, Thu, Sep 22, 1921 |
 Detroit Tigers
5
 at New York Yankees
12
|
Final | Game page: Detroit Tigers at New York Yankees, Thu, Sep 22, 1921 |
 Philadelphia Phillies
4
 at Cincinnati Reds
5
|
Final (10) | Game page: Philadelphia Phillies at Cincinnati Reds, Thu, Sep 22, 1921 |
| St. Louis Browns 5 at Philadelphia Athletics 0 | Final | Game page: St. Louis Browns at Philadelphia Athletics, Thu, Sep 22, 1921 |
|
Brooklyn Robins
2
at Pittsburgh Pirates
0
|
Final | Game page: Brooklyn Robins at Pittsburgh Pirates, Thu, Sep 22, 1921 |
| St. Louis Browns 4 at Philadelphia Athletics 3 | Final | Game page: St. Louis Browns at Philadelphia Athletics, Thu, Sep 22, 1921 |