MLB Games on Tuesday, April 21, 1925
4 games on Tuesday, April 21, 1925. Start times are Eastern Time.
| Matchup | Status | Details |
|---|---|---|
 Boston Red Sox
1
 at New York Yankees
5
|
Final | Game page: Boston Red Sox at New York Yankees, Tue, Apr 21, 1925 |
Cleveland Indians
3
 at Detroit Tigers
4
|
Final | Game page: Cleveland Indians at Detroit Tigers, Tue, Apr 21, 1925 |
| Washington Senators 6 at Philadelphia Athletics 2 | Final | Game page: Washington Senators at Philadelphia Athletics, Tue, Apr 21, 1925 |
 Chicago White Sox
8
at St. Louis Browns
9
|
Final | Game page: Chicago White Sox at St. Louis Browns, Tue, Apr 21, 1925 |