MLB Games on Wednesday, April 22, 1925
8 games on Wednesday, April 22, 1925. Start times are Eastern Time.
| Matchup | Status | Details |
|---|---|---|
Brooklyn Robins
7
 at Philadelphia Phillies
8
|
Final | Game page: Brooklyn Robins at Philadelphia Phillies, Wed, Apr 22, 1925 |
| Boston Braves 5 at New York Giants 6 | Final | Game page: Boston Braves at New York Giants, Wed, Apr 22, 1925 |
 Chicago Cubs
1
 at Pittsburgh Pirates
6
|
Final | Game page: Chicago Cubs at Pittsburgh Pirates, Wed, Apr 22, 1925 |
 New York Yankees
1
at Washington Senators
10
|
Final | Game page: New York Yankees at Washington Senators, Wed, Apr 22, 1925 |
Philadelphia Athletics
6
 at Boston Red Sox
5
|
Final (11) | Game page: Philadelphia Athletics at Boston Red Sox, Wed, Apr 22, 1925 |
| St. Louis Browns 3 at Cleveland Indians 2 | Final (10) | Game page: St. Louis Browns at Cleveland Indians, Wed, Apr 22, 1925 |
 Cincinnati Reds
3
 at St. Louis Cardinals
12
|
Final | Game page: Cincinnati Reds at St. Louis Cardinals, Wed, Apr 22, 1925 |
 Detroit Tigers
1
 at Chicago White Sox
3
|
Final | Game page: Detroit Tigers at Chicago White Sox, Wed, Apr 22, 1925 |