MLB Games on Wednesday, September 17, 2025

15 games on Wednesday, September 17, 2025. Start times are Eastern Time.

MLB games on Wednesday, September 17, 2025
Matchup	Status	Details
Chicago Cubs 8 at Pittsburgh Pirates 4	Final	Game page: Chicago Cubs at Pittsburgh Pirates, Wed, Sep 17, 2025
Cincinnati Reds 6 at St. Louis Cardinals 2	Final	Game page: Cincinnati Reds at St. Louis Cardinals, Wed, Sep 17, 2025
Baltimore Orioles 3 at Chicago White Sox 1	Final	Game page: Baltimore Orioles at Chicago White Sox, Wed, Sep 17, 2025
San Francisco Giants 5 at Arizona Diamondbacks 1	Final (11)	Game page: San Francisco Giants at Arizona Diamondbacks, Wed, Sep 17, 2025
Atlanta Braves 9 at Washington Nationals 4	Final	Game page: Atlanta Braves at Washington Nationals, Wed, Sep 17, 2025
Cleveland Guardians 4 at Detroit Tigers 0	Final	Game page: Cleveland Guardians at Detroit Tigers, Wed, Sep 17, 2025
Athletics 4 at Boston Red Sox 5	Final (10)	Game page: Athletics at Boston Red Sox, Wed, Sep 17, 2025
Toronto Blue Jays 1 at Tampa Bay Rays 2	Final	Game page: Toronto Blue Jays at Tampa Bay Rays, Wed, Sep 17, 2025
San Diego Padres 7 at New York Mets 4	Final	Game page: San Diego Padres at New York Mets, Wed, Sep 17, 2025
New York Yankees 10 at Minnesota Twins 5	Final	Game page: New York Yankees at Minnesota Twins, Wed, Sep 17, 2025
Seattle Mariners 5 at Kansas City Royals 7	Final	Game page: Seattle Mariners at Kansas City Royals, Wed, Sep 17, 2025
Los Angeles Angels 2 at Milwaukee Brewers 9	Final	Game page: Los Angeles Angels at Milwaukee Brewers, Wed, Sep 17, 2025
Texas Rangers 2 at Houston Astros 5	Final	Game page: Texas Rangers at Houston Astros, Wed, Sep 17, 2025
Miami Marlins 8 at Colorado Rockies 4	Final	Game page: Miami Marlins at Colorado Rockies, Wed, Sep 17, 2025
Philadelphia Phillies 0 at Los Angeles Dodgers 5	Final	Game page: Philadelphia Phillies at Los Angeles Dodgers, Wed, Sep 17, 2025