San Francisco Giants at Pittsburgh Pirates
· PNC Park, Pittsburgh · Regular Season · Time TBD
Matchup
The San Francisco Giants visit the Pittsburgh Pirates on Wednesday, April 21, 2027.
2027 season series
Every San Francisco Giants and Pittsburgh Pirates game in the 2027 season
| Matchup |
Status |
Details |
 San Francisco Giants
 at Pittsburgh Pirates
|
Time TBD
|
Game page: San Francisco Giants at Pittsburgh Pirates, Tue, Apr 20, 2027
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San Francisco Giants
at Pittsburgh Pirates
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Time TBD
|
Game page: San Francisco Giants at Pittsburgh Pirates, Wed, Apr 21, 2027
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San Francisco Giants
at Pittsburgh Pirates
|
Time TBD
|
Game page: San Francisco Giants at Pittsburgh Pirates, Thu, Apr 22, 2027
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Pittsburgh Pirates
at San Francisco Giants
|
Time TBD
|
Game page: Pittsburgh Pirates at San Francisco Giants, Fri, Sep 10, 2027
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Pittsburgh Pirates
at San Francisco Giants
|
Time TBD
|
Game page: Pittsburgh Pirates at San Francisco Giants, Sat, Sep 11, 2027
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Pittsburgh Pirates
at San Francisco Giants
|
Time TBD
|
Game page: Pittsburgh Pirates at San Francisco Giants, Sun, Sep 12, 2027
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Other MLB games on Apr 21
Other MLB games on Wednesday, April 21, 2027
| Matchup |
Status |
Details |
 Cleveland Guardians
 at Toronto Blue Jays
|
Time TBD
|
Game page: Cleveland Guardians at Toronto Blue Jays, Wed, Apr 21, 2027
|
 Milwaukee Brewers
 at New York Yankees
|
Time TBD
|
Game page: Milwaukee Brewers at New York Yankees, Wed, Apr 21, 2027
|
 Cincinnati Reds
 at Miami Marlins
|
Time TBD
|
Game page: Cincinnati Reds at Miami Marlins, Wed, Apr 21, 2027
|
 Tampa Bay Rays
 at Boston Red Sox
|
Time TBD
|
Game page: Tampa Bay Rays at Boston Red Sox, Wed, Apr 21, 2027
|
 Seattle Mariners
 at Texas Rangers
|
Time TBD
|
Game page: Seattle Mariners at Texas Rangers, Wed, Apr 21, 2027
|
 Minnesota Twins
 at St. Louis Cardinals
|
Time TBD
|
Game page: Minnesota Twins at St. Louis Cardinals, Wed, Apr 21, 2027
|
 Detroit Tigers
 at Chicago White Sox
|
Time TBD
|
Game page: Detroit Tigers at Chicago White Sox, Wed, Apr 21, 2027
|
 San Diego Padres
 at Colorado Rockies
|
Time TBD
|
Game page: San Diego Padres at Colorado Rockies, Wed, Apr 21, 2027
|
 Houston Astros
 at Los Angeles Angels
|
Time TBD
|
Game page: Houston Astros at Los Angeles Angels, Wed, Apr 21, 2027
|
 New York Mets
 at Athletics
|
Time TBD
|
Game page: New York Mets at Athletics, Wed, Apr 21, 2027
|
 Chicago Cubs
 at Arizona Diamondbacks
|
Time TBD
|
Game page: Chicago Cubs at Arizona Diamondbacks, Wed, Apr 21, 2027
|
 Kansas City Royals
 at Baltimore Orioles
|
Time TBD
|
Game page: Kansas City Royals at Baltimore Orioles, Wed, Apr 21, 2027
|
 Los Angeles Dodgers
 at Philadelphia Phillies
|
6:40 PM ET
|
Game page: Los Angeles Dodgers at Philadelphia Phillies, Wed, Apr 21, 2027
|
 Washington Nationals
 at Atlanta Braves
|
7:15 PM ET
|
Game page: Washington Nationals at Atlanta Braves, Wed, Apr 21, 2027
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