Houston Astros at St. Louis Cardinals
Final score
The St. Louis Cardinals beat the Houston Astros 3–1 on Thursday, May 21, 1981 at home.
| Team | Runs | 1981 record |
|---|---|---|
 Houston Astros |
1 | 61-49 |
 at St. Louis Cardinals |
3 | 59-43-1 |
1981 season series
| Matchup | Status | Details |
|---|---|---|
|
St. Louis Cardinals
3
at Houston Astros
2
|
Final (10) | Game page: St. Louis Cardinals at Houston Astros, Tue, May 12, 1981 |
|
St. Louis Cardinals
0
at Houston Astros
3
|
Final | Game page: St. Louis Cardinals at Houston Astros, Wed, May 13, 1981 |
|
St. Louis Cardinals
7
at Houston Astros
6
|
Final | Game page: St. Louis Cardinals at Houston Astros, Thu, May 14, 1981 |
|
Houston Astros
12
at St. Louis Cardinals
15
|
Final | Game page: Houston Astros at St. Louis Cardinals, Tue, May 19, 1981 |
|
Houston Astros
4
at St. Louis Cardinals
3
|
Final (11) | Game page: Houston Astros at St. Louis Cardinals, Wed, May 20, 1981 |
|
Houston Astros
1
at St. Louis Cardinals
3
|
Final | Game page: Houston Astros at St. Louis Cardinals, Thu, May 21, 1981 |
Other MLB games on May 21
| Matchup | Status | Details |
|---|---|---|
 Cincinnati Reds
1
 at Chicago Cubs
5
|
Final | Game page: Cincinnati Reds at Chicago Cubs, Thu, May 21, 1981 |
 Minnesota Twins
2
 at Milwaukee Brewers
8
|
Final | Game page: Minnesota Twins at Milwaukee Brewers, Thu, May 21, 1981 |
California Angels
2
 at Baltimore Orioles
0
|
Final | Game page: California Angels at Baltimore Orioles, Thu, May 21, 1981 |
Oakland Athletics
0
 at Boston Red Sox
3
|
Final | Game page: Oakland Athletics at Boston Red Sox, Thu, May 21, 1981 |
 Seattle Mariners
6
at Cleveland Indians
3
|
Final | Game page: Seattle Mariners at Cleveland Indians, Thu, May 21, 1981 |